N-Phenylpyrrolidine-1-carbothioamide

Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives.

The reaction of 1-adamantyl isothiocyanate 4 with the various cyclic secondary amines yielded the corresponding N-(1-adamantyl)carbothioamides 5a-e, 6, 7, 8a-c and 9. Similarly, the reaction of 4 with piperazine and trans-2,5-dimethylpiperazine in 2:1 molar ratio yielded the corresponding N,N'-bis(1-adamantyl)piperazine-1,4-dicarbothioamides 10a and 10b, respectively. The reaction of N-(1-adama...

Synthesis of 3-bromo-4-isobutyloxyphenyl carbothioamide

3-bromo-4-isobutyloxyphenyl carbothioamide 1 is an important intermediate in many biologically active compounds such as febuxostat. In this work, a rapid synthetic method for compound 1 was established. The compound 1 was synthesized from the commercially available 4-hydroxybenzonitrile 2 through three steps including bromination, oxyalkylation and thioamidation. The structure was confirmed by ...

On the nature of solutions of the difference equation $mathbf{x_{n+1}=x_{n}x_{n-3}-1}$

We investigate the long-term behavior of solutions of the difference equation[ x_{n+1}=x_{n}x_{n-3}-1 ,, n=0 ,, 1 ,, ldots ,, ]noindent where the initial conditions $x_{-3} ,, x_{-2} ,, x_{-1} ,, x_{0}$ are real numbers.  In particular, we look at the periodicity and asymptotic periodicity of solutions, as well as the existence of unbounded solutions.

Selective and catalytic arylation of N-phenylpyrrolidine: sp3 C-H bond functionalization in the absence of a directing group.

We herein describe our studies on arylation of N-phenylpyrrolidine, which led to the development of a new transformation for the direct and selective arylation of sp3 C-H bonds in the absence of a directing group. In this method, Ru(H)2(CO)(PCy3)3 4 was used as the catalyst, and preliminary mechanistic studies suggested that Ru(Ph)(I)(CO)(PCy3)2 5 is the key intermediate of the catalytic cycle....

On the Rational Recursive Sequence X_{N+1}=ƔX_{N-K}+(AX_N+BX_{N-K})⁄(CX_N-DX_{N-K})